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Los steres de cidos grasos (de la CoA) se forman casi exclusivamente en el citosol y no se transportan a travs de la membrana, inhibe tambin enzimas de ciclo de Krebs, por ende la oxidacin de cidos grasos requiere la formacin de acilcarnitinas y su translocacin hacia las mitocondrias, donde se vuelven a formar steres de CoA y se metabolizan produciendo energa
inhibiting the enzymes that played a role in the production of ROS (e.g., xanthine oxidase)
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To help provide insights into the potential role of oral semaglutide in current T2D management, this article aims to discuss the pharmacology of oral semaglutide, review the current clinical evidence on the efficacy and safety of this agent from the extensive phase III PIONEER clinical trial program in patients with T2D, and describe findings from initial cost-effectiveness studies
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