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However, naturally produced GLP-1 has a very short half-lifeapproximately 2 to 3 minutesbecause it is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4)

Eating smaller, more frequent meals and avoiding high-fat foods in the hours after injection can help

Human carboxylesterase 2 reverses obesity-induced diacylglycerol accumulation and glucose intolerance

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