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Ferroptosis is involved in regulating the occurrence and progression of diseases such as cancer, respiratory system diseases, cardiovascular system diseases, diabetes mellitus, and urinary system diseases and plays a key role in disease treatment (11) ( Figure 1 )
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GSH biosynthesis is generally performed by two consecutive ATP-consuming reactions catalyzed by -glutamylcysteine synthetase (-GCS, GSHI) and glutathione synthetase (GS, GSHII) from three precursors in microorganisms: l-glutamate, l-cysteine, and glycine [1]
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