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Alkaliptosis: a new weapon for cancer therapy

A.Lam-GalvezB

This kind of trial would be the perfect opportunity to conduct additional research on any refractory or recurrent tumors that may develop and to correlate these findings with patient characteristics so as to both improve the treatment of such tumors and, possibly, screen patients before they undergo PDT and provide them with personalized information about the possibility of treatment failure

The brain, sensing a drop in blood pressure and oxygen, initiates a "fight or flight" surge of adrenaline and norepinephrine, which causes the rapid, pounding heart rate (tachycardia), severe lightheadedness, and physical tremors associated with orthostatic intolerance

The first readout, TRIUMPH-1 (obesity), was reported on 21 May 2026, with 28.3% mean weight loss at 80 weeks in the 12mg cohort (Pharmaceutical Journal)