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The most compelling campaigns anchor messaging in real-world outcomes: For HCPs, the story starts with data cardiovascular risk reduction, sustained weight loss, lower A1C, and improved patient vitality which drive practice change and position these therapies as more than metabolic tools

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observed that in T2DM patients (mean age: 64.9 years) treated with subcutaneous semaglutide, reductions in the SMI were smaller than those in the fat mass index (FMI) [56], and the findings suggest a preservation of muscle strength and muscle quality

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Here's where it gets interesting: some of the mechanisms tirzepatide corrects (insulin resistance, chronic inflammation, leptin excess) are the very mechanisms driving obesity-related low supply