switching from semaglutide to retatrutide vs Tirzepatide vs Retatrutide: 2026 Chicago Guide CagriSema vs Retatrutide: Amylin/GLP-1 Combination

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Villareal DT, Apovian CM, Kushner RF, Klein S, American Society for Nutrition

Hypothalamic dysfunction and altered hypothalamic structure impair satiety response, with delayed or even absent activation of satiety centers following glucose or food intake (710)

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Clinical observations suggest that semaglutide may reduce the frequency and intensity of IBS symptoms by slowing gastric emptying in a controlled manner and decreasing intestinal hypersensitivity