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Idiosyncratic (type B) injury occurs without warning, when agents cause non-predictable hepatotoxicity in susceptible individuals, which is not related to dose and has a variable latency period
The anti-inflammatory mechanisms in more detail
For this purpose, we firstly analyzed the effects of GLP-1 on HPG axis, particularly considering its actions at both central (hypothalamus and pituitary) and peripheral (ovary) levels
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A published report has shown that the NF-B member, RelB, plays a role in upregulating GPX4 expression and suppressing ferroptosis, thereby increasing the resistance of ER+ breast cancer cells to Tamoxifen [32]
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