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O SURMOUNT-1 publicado no New England Journal of Medicine em julho de 2022, comparou o tratamento com Zepbound em doses subcutneas semanais de 5 mg, 10 mg e 15 mg com a administrao de placebo, ao longo de 72 semanas, envolvendo 2539 pacientes sem diabetes, todos eles com sobrepeso (IMC 27 kg/m) ou obesidade

By stimulating insulin release, reducing glucose production, slowing gastric emptying, and supporting appetite control, it delivers comprehensive metabolic benefits through a simple weekly injection

In addition, they inhibit glucagon secretion and have other systemic effects, such as changes in intestinal transit and gastric emptying, as well as effects on the central nervous system, altering the sensation of satiety and appetite [8]

The Bottom Line Breakfast can feel harder to manage on a GLP-1, especially with low appetite or nausea in the mix

Your decision should be based on your appetite patterns, cravings, energy needs, budget, and what feels emotionally supportive