Weight loss is a huge concern in the modern world, with nearly 82% of Americans suffering from at least being overweight, if not obese, or having severe obesity
Appearing on TBPN, Andrew Huberman said retatrutide could be the peptide that changes everything. Now in Phase III clinical trials, its shown up to 30% body weight loss in under a year, with signs of muscle preservation
But its work doesnt stop there
In line with this notion, pharmacologic or genetic suppression of GLP-1R in the lateral septum attenuates the ability of cocaine to activate the mesolimbic dopamine system, as assessed by hyperactivity, reward in the CPP test, and dopamine enhancement in the NAc ( via arachidonic acid and the increased expression of the dopamine transporter within the lateral septum ( Although the vast majority of studies have revealed interactions between cocaine responses and GLP-1R, some studies have reported correlations between the responses to cocaine and the plasma levels of GLP-1
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