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An overall schematic of the common pathological microenvironment of scar formation and AD (including intercellular crosstalk, fibrotic remodeling, immune dysregulation, and redox imbalance) and various nanotechnological strategies to fundamentally reprogram this dysregulated state are summarized in Fig

Propolis and some of its constituents down-regulate DNA synthesis and inflammatory cytokine production but induce TGF-beta1 production of human immune cells

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Glutathione and its role in immune function

In addition, butyrate can activate the signaling pathway mediated by G protein-coupled receptors (GPRs), further inhibiting the downstream MEK-ERK and NF-B pathways