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This possible side effect was highlighted by an analysis of data from the PIONEER and SUSTAIN efficacy trials
Neither medication is clearly safer than the other
The reasons for this difference are not fully understood, but it is generally believed that the blood glucose-lowering effect of semaglutide, leading to reduced urinary glucose loss, may result in relative energy retention, which may reduce weight loss [107]
#Pharmacy #RegulatoryAffairs #Pharmaceuticals #WeightLoss #GLP1 #Healthcare #Innovation #EliLilly To view or add a comment, sign in More Relevant Posts Chronic Kidney Disease (CKD) affects more than 10% of the global population, often progressing silently until advanced stages
The subsequent phase 3 trial of tirzepatide demonstrated more effective reductions in the glycated hemoglobin levels and body weight, along with greater overall improvements in the lipid profile compared to semaglutide in patients with T2DM, elevating incretin therapeutic agents to a new level (112)
