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A higher HRV indicates a more resilient and adaptable nervous system, capable of calming the hyperadrenergic state that drives the severe tachycardia and palpitations experienced by POTS patients

In most cases, these changes are thought to be related to weight loss, hormonal adjustments, improved insulin sensitivity, and changes in ovulation rather than a direct effect of the medication on the menstrual cycle

doi:10.1016/j.jad.2009.11.008

Recommended Daily Limits For most adults, the recommended caffeine limit is below 400 milligrams (mg) per day, roughly equivalent to four 8-ounce cups of coffee

Pharma-grade factories work under FDA-inspected rules