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Limitations and Drawbacks Gastrointestinal Side Effects: Common side effects include nausea, vomiting, diarrhea, and constipation, which may reduce adherence, especially in those already experiencing GI issues from alcohol use

Both products were marketed and sold without prescriptions, without medical oversight, and without the regulatory framework that governs legitimate pharmaceutical distribution

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Zhang Y, Li Q, Wang J, Cheng F, Huang X, Cheng Y, Wang K (2016) Polysaccharide from Lentinus edodes combined with oxaliplatin possesses the synergy and attenuation effect in hepatocellular carcinoma