The results from the new GPx-Tiron method demonstrate exceptional analytical performance, with a linear response over a wide range of GPx activity levels (5500 U/l) and high sensitivity, evidenced by low LOD and LOQ
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The researchers suggest that during evaluation, the peptide increased cell viability and migration and increased tube formation on matrices, which is commonly exposed to research models as a lab proxy for angiogenic behavior
However, when ALOX12 was depleted, the expression of p53 and SLC7A11 was not affected [19]