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These changes were paralleled by marked decreases in total, abdominal, leg, and arm fat percentage, along with increases in FFM and total body muscle percentage

FDA approvals are increasing Medicare coverage, but it is still a long way from covering all recipients with obesity

We used R software (version 3.2.2, Free Software Foundation, Inc, Boston, MA), SAS (version 9.2, SAS Inc., Cary, NC), and Stata/MP (version 16, StataCorp, College Station, TX)

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Metformin is not recommended when eGFR is consistently less than 30 mL/min/1.73 m 2 , and in LEADER, SUSTAIN 6 and PIONEER 6, some of those who were not taking metformin had lower eGFRs