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This complex metabolic disorder is accompanied by an increase in local and systemic inflammatory mediators, such as proinflammatory cytokines [e.g., interleukin (IL)-6 and IL-8 and tumor necrosis factor-alpha (TNF-)] [9, 10]

Dosage Range: The standard clinical dosage ranges from 1.25 mg to 2.0 mg, depending on patient response and tolerance

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Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic -cells