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Lower pricing for both the Medicare and consumer cash-pay channel as a result of MFN, as well as patent expiries in jurisdictions including Brazil, Canada and China will "probably lead to a decreasing top line," said Hansen

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Gomez-Lechon, M

The Medicines and Healthcare products Regulatory Agency (MHRA) and the European Medicines Agency (EMA) have reviewed the available safety data and approved tirzepatide for use in the UK and Europe, indicating an acceptable benefit-risk profile based on current evidence

Phase Phase 2 - Early escalation Weeks Weeks 5-8 Weekly dose 0.5 mg What to expect First meaningful dose