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Individuals with two copies (homozygous) have about 3040% of normal enzyme activity

Other possible causes of hematochezia include: Hemorrhoids : internal or external Inflammation of the colon : possibly due to inflammatory bowel disease (IBD) Infection : due to ulcerative colitis or some other condition Vascular lesions : also known as angiodysplasia The most common causes of melena are stomach ulcers and inflammation of the esophagus or stomach

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