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, markedly less damaged neurons in most severely injuried areas) is in accord with: its neuroprotective properties (22, 34), consistent antagonization of different central disturbances (16-23, 34), brain 5-HT synthesis and antagonization of serotonin-syndrome in rats based on region-specific influence on the brain given peripherally either acutely or chronically ( i.e
In addition to its role in energy production via the TCA cycle, -KG plays a central role in amino acid synthesis, redox balance, and the regulation of cell signaling
PMID: 52 FishmanCEWalsheCClaridgeTWitekSPandyaKChristieJDet al
6 and 7, Supplementary Tables 4-8 and Supplementary Movie 1